The Jayhawks gave it their best effort, but ultimately were no match for No. 23 Iowa State in a 52-22 loss Saturday afternoon at David Booth Kansas Memorial Stadium.
The Cyclones, who were favored by more than four touchdowns entering this game, bounced back from its lone Big 12 loss of the season to improve to 4-2 on the year, including 4-1 in league action.
Kansas is now 0-6 overall, which includes five lopsided losses against conference foes.
KU will travel to Oklahoma at 2:30 p.m. Saturday.