KU researchers pursue innovations

By Regina Cassell     Mar 4, 2002

Musical depictions of an epileptic seizure aren’t the only imaginative or important research going on at Kansas University Medical Center. Other projects could lead to a cure for ovarian cancer, lessen the incidence of heart attacks or help the millions of people who suffer high blood pressure.

Dr. Patrice Delafontaine, head of cardiac research, is leading a research team that has determined that the decline in proteins in smooth muscle cells could contribute to weakening of the vascular system and play a part in heart attacks and strokes.

Dr. Thomas DuBose, professor and chair of internal medicine, has identified a family of proteins in the kidney that play a critical role in regulating potassium in the blood. Irregular levels can lead to high blood pressure. His team also has found that certain genetic defects can result in an inherited form of renal tubular acidosis.

Paul Terranova, professor of molecular and integrative physiology; Katherine Roby, assistant research professor of anatomy and cell biology, and Dr. Valerie Montgomery Rice, assistant professor of reproductive endocrinology, are working toward finding a cause for ovarian cancer. Roby is attempting to combine low-dose chemotherapies with gene therapy to treat ovarian cancer.

Dr. Jared Grantham, professor of nephrology, is determining whether magnetic-imaging scans can accurately measure the progression of an inherited form of polycystic kidney disease.

Paul Cheney, director of the Mental Retardation Research Center, is leading a group of researchers trying to determine how AIDS damages brain neurons.

Travis Thompson, director of the Institute for Child Development, is working to determine the link between a gene defect and Prader Willi Syndrome, an eating and compulsive behavior disorder.

Joseph Tash, associate professor of molecular and integrative physiology, is studying effects of gravity on the motility of sperm, which could affect the possibilities of life in space and provide benefits to ranchers and poultry farmers.

KU Medical Center researchers received $53.5 million in funding from the National Institutes of Health during 2001, up from $43.6 million in 2000.

KU researchers pursue innovations

By Regina Cassell     Mar 4, 2002

Musical depictions of an epileptic seizure aren’t the only imaginative or important research going on at Kansas University Medical Center. Other projects could lead to a cure for ovarian cancer, lessen the incidence of heart attacks or help the millions of people who suffer high blood pressure.

Dr. Patrice Delafontaine, head of cardiac research, is leading a research team that has determined that the decline in proteins in smooth muscle cells could contribute to weakening of the vascular system and play a part in heart attacks and strokes.

Dr. Thomas DuBose, professor and chair of internal medicine, has identified a family of proteins in the kidney that play a critical role in regulating potassium in the blood. Irregular levels can lead to high blood pressure. His team also has found that certain genetic defects can result in an inherited form of renal tubular acidosis.

Paul Terranova, professor of molecular and integrative physiology; Katherine Roby, assistant research professor of anatomy and cell biology, and Dr. Valerie Montgomery Rice, assistant professor of reproductive endocrinology, are working toward finding a cause for ovarian cancer. Roby is attempting to combine low-dose chemotherapies with gene therapy to treat ovarian cancer.

Dr. Jared Grantham, professor of nephrology, is determining whether magnetic-imaging scans can accurately measure the progression of an inherited form of polycystic kidney disease.

Paul Cheney, director of the Mental Retardation Research Center, is leading a group of researchers trying to determine how AIDS damages brain neurons.

Travis Thompson, director of the Institute for Child Development, is working to determine the link between a gene defect and Prader Willi Syndrome, an eating and compulsive behavior disorder.

Joseph Tash, associate professor of molecular and integrative physiology, is studying effects of gravity on the motility of sperm, which could affect the possibilities of life in space and provide benefits to ranchers and poultry farmers.

KU Medical Center researchers received $53.5 million in funding from the National Institutes of Health during 2001, up from $43.6 million in 2000.

KU researchers pursue innovations

By Regina Cassell     Mar 4, 2002

Musical depictions of an epileptic seizure aren’t the only imaginative or important research going on at Kansas University Medical Center. Other projects could lead to a cure for ovarian cancer, lessen the incidence of heart attacks or help the millions of people who suffer high blood pressure.

Dr. Patrice Delafontaine, head of cardiac research, is leading a research team that has determined that the decline in proteins in smooth muscle cells could contribute to weakening of the vascular system and play a part in heart attacks and strokes.

Dr. Thomas DuBose, professor and chair of internal medicine, has identified a family of proteins in the kidney that play a critical role in regulating potassium in the blood. Irregular levels can lead to high blood pressure. His team also has found that certain genetic defects can result in an inherited form of renal tubular acidosis.

Paul Terranova, professor of molecular and integrative physiology; Katherine Roby, assistant research professor of anatomy and cell biology, and Dr. Valerie Montgomery Rice, assistant professor of reproductive endocrinology, are working toward finding a cause for ovarian cancer. Roby is attempting to combine low-dose chemotherapies with gene therapy to treat ovarian cancer.

Dr. Jared Grantham, professor of nephrology, is determining whether magnetic-imaging scans can accurately measure the progression of an inherited form of polycystic kidney disease.

Paul Cheney, director of the Mental Retardation Research Center, is leading a group of researchers trying to determine how AIDS damages brain neurons.

Travis Thompson, director of the Institute for Child Development, is working to determine the link between a gene defect and Prader Willi Syndrome, an eating and compulsive behavior disorder.

Joseph Tash, associate professor of molecular and integrative physiology, is studying effects of gravity on the motility of sperm, which could affect the possibilities of life in space and provide benefits to ranchers and poultry farmers.

KU Medical Center researchers received $53.5 million in funding from the National Institutes of Health during 2001, up from $43.6 million in 2000.

KU researchers pursue innovations

By Regina Cassell     Mar 4, 2002

Musical depictions of an epileptic seizure aren’t the only imaginative or important research going on at Kansas University Medical Center. Other projects could lead to a cure for ovarian cancer, lessen the incidence of heart attacks or help the millions of people who suffer high blood pressure.

Dr. Patrice Delafontaine, head of cardiac research, is leading a research team that has determined that the decline in proteins in smooth muscle cells could contribute to weakening of the vascular system and play a part in heart attacks and strokes.

Dr. Thomas DuBose, professor and chair of internal medicine, has identified a family of proteins in the kidney that play a critical role in regulating potassium in the blood. Irregular levels can lead to high blood pressure. His team also has found that certain genetic defects can result in an inherited form of renal tubular acidosis.

Paul Terranova, professor of molecular and integrative physiology; Katherine Roby, assistant research professor of anatomy and cell biology, and Dr. Valerie Montgomery Rice, assistant professor of reproductive endocrinology, are working toward finding a cause for ovarian cancer. Roby is attempting to combine low-dose chemotherapies with gene therapy to treat ovarian cancer.

Dr. Jared Grantham, professor of nephrology, is determining whether magnetic-imaging scans can accurately measure the progression of an inherited form of polycystic kidney disease.

Paul Cheney, director of the Mental Retardation Research Center, is leading a group of researchers trying to determine how AIDS damages brain neurons.

Travis Thompson, director of the Institute for Child Development, is working to determine the link between a gene defect and Prader Willi Syndrome, an eating and compulsive behavior disorder.

Joseph Tash, associate professor of molecular and integrative physiology, is studying effects of gravity on the motility of sperm, which could affect the possibilities of life in space and provide benefits to ranchers and poultry farmers.

KU Medical Center researchers received $53.5 million in funding from the National Institutes of Health during 2001, up from $43.6 million in 2000.

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