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Dayton, Ohio At Dayton, Ohio, Terrence Williams had 24 points and 15 rebounds as Louisville, the overall No. 1 seed, reached the round of 16 for the second straight year.
Louisville (30-5) will play 12th-seeded Arizona on Friday in Indianapolis.
Siena (27-8) overcame a 12-point deficit in the second half and led 63-59 with 7:20 left.