Baylor overcame a 21-point deficit in the fourth quarter, rallying to take down Kansas, 31-30, in overtime on Saturday at Memorial Stadium.
KU's defense allowed 89-, 98- and 80-yard touchdown drives to Baylor in the fourth quarter, as the Bears tied it up with 4:07 left on a 67-yard touchdown reception by Tevin Reese.
In overtime, Reese scored first on a 14-yard TD reception.
KU's Tim Biere followed with a 25-yard TD catch, and KU coach Turner Gill decided to go for two and the win. Jordan Webb's fade pass to Biere fell incomplete, and Baylor's players rushed onto the field to celebrate the victory.
After throwing for just 79 yards in the first half, Griffin finished with 312 yards passing while adding 103 yards rushing.
Darrian Miller led KU with 24 rushes for 147 yards.
KU (2-8) will travel to face Texas A&M on Nov. 19.
Baylor comes back from 21 down in the fourth quarter to win.